Review





Similar Products

eht1864  (MedChemExpress)
94
MedChemExpress eht1864
(A) Signaling schematic representing the regulation by PIP5K1C/Rho/ROCK/Rac signaling. (B-I) Average migration of NE-1 and KO-BRCA1 pools in transwell migration assay. Vehicle (ethanol), 10nM R5020, or 10nM R5020 + inhibitor combo treatment for 6-hour migration timepoint, which includes a prior 24-hour pre-treatment of either vehicle (ethanol), 10nM R5020, or 10nM R5020 + inhibitor treatment, respectively. 10% FBS used as chemoattractant. Representative bright-field images to the side of each graph taken at 100µm magnification. (B-C) PIP5K1C Inhibitor: 10µM UNC3230. Graph represents the mean ± SD, * p = 0.0248, ** p ≤ 0.0082, *** p = 0.0001, **** p < 0.0001. (D-E) Rho Inhibitor: 1µg/ml CT04 (Note: no inhibitor pre-treatment). Graph represents the mean ± SD, * p = 0.0285, ** p ≤ 0.0095, **** p < 0.0001. (F-G) ROCK Inhibitor: 10µM Y-27632. Graph represents the mean ± SD, * p ≤ 0.0384, ** p ≤ 0.0016, **** p < 0.0001. (H-1) Rac Inhibitor: 25µM <t>EHT1864.</t> Graph represents the mean ± SD, * p = 0.0120, *** p = 0.0002, **** p < 0.0001.
Eht1864, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/eht1864/product/MedChemExpress
Average 94 stars, based on 1 article reviews
eht1864 - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier
eht1864  (TargetMol)
94
TargetMol eht1864
(A) Signaling schematic representing the regulation by PIP5K1C/Rho/ROCK/Rac signaling. (B-I) Average migration of NE-1 and KO-BRCA1 pools in transwell migration assay. Vehicle (ethanol), 10nM R5020, or 10nM R5020 + inhibitor combo treatment for 6-hour migration timepoint, which includes a prior 24-hour pre-treatment of either vehicle (ethanol), 10nM R5020, or 10nM R5020 + inhibitor treatment, respectively. 10% FBS used as chemoattractant. Representative bright-field images to the side of each graph taken at 100µm magnification. (B-C) PIP5K1C Inhibitor: 10µM UNC3230. Graph represents the mean ± SD, * p = 0.0248, ** p ≤ 0.0082, *** p = 0.0001, **** p < 0.0001. (D-E) Rho Inhibitor: 1µg/ml CT04 (Note: no inhibitor pre-treatment). Graph represents the mean ± SD, * p = 0.0285, ** p ≤ 0.0095, **** p < 0.0001. (F-G) ROCK Inhibitor: 10µM Y-27632. Graph represents the mean ± SD, * p ≤ 0.0384, ** p ≤ 0.0016, **** p < 0.0001. (H-1) Rac Inhibitor: 25µM <t>EHT1864.</t> Graph represents the mean ± SD, * p = 0.0120, *** p = 0.0002, **** p < 0.0001.
Eht1864, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/eht1864/product/TargetMol
Average 94 stars, based on 1 article reviews
eht1864 - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier
eht 1864  (MedChemExpress)
94
MedChemExpress eht 1864
(A) Signaling schematic representing the regulation by PIP5K1C/Rho/ROCK/Rac signaling. (B-I) Average migration of NE-1 and KO-BRCA1 pools in transwell migration assay. Vehicle (ethanol), 10nM R5020, or 10nM R5020 + inhibitor combo treatment for 6-hour migration timepoint, which includes a prior 24-hour pre-treatment of either vehicle (ethanol), 10nM R5020, or 10nM R5020 + inhibitor treatment, respectively. 10% FBS used as chemoattractant. Representative bright-field images to the side of each graph taken at 100µm magnification. (B-C) PIP5K1C Inhibitor: 10µM UNC3230. Graph represents the mean ± SD, * p = 0.0248, ** p ≤ 0.0082, *** p = 0.0001, **** p < 0.0001. (D-E) Rho Inhibitor: 1µg/ml CT04 (Note: no inhibitor pre-treatment). Graph represents the mean ± SD, * p = 0.0285, ** p ≤ 0.0095, **** p < 0.0001. (F-G) ROCK Inhibitor: 10µM Y-27632. Graph represents the mean ± SD, * p ≤ 0.0384, ** p ≤ 0.0016, **** p < 0.0001. (H-1) Rac Inhibitor: 25µM <t>EHT1864.</t> Graph represents the mean ± SD, * p = 0.0120, *** p = 0.0002, **** p < 0.0001.
Eht 1864, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/eht 1864/product/MedChemExpress
Average 94 stars, based on 1 article reviews
eht 1864 - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier
hy 100462 eht 1864 medchemexpress  (MedChemExpress)
93
MedChemExpress hy 100462 eht 1864 medchemexpress
(A) Signaling schematic representing the regulation by PIP5K1C/Rho/ROCK/Rac signaling. (B-I) Average migration of NE-1 and KO-BRCA1 pools in transwell migration assay. Vehicle (ethanol), 10nM R5020, or 10nM R5020 + inhibitor combo treatment for 6-hour migration timepoint, which includes a prior 24-hour pre-treatment of either vehicle (ethanol), 10nM R5020, or 10nM R5020 + inhibitor treatment, respectively. 10% FBS used as chemoattractant. Representative bright-field images to the side of each graph taken at 100µm magnification. (B-C) PIP5K1C Inhibitor: 10µM UNC3230. Graph represents the mean ± SD, * p = 0.0248, ** p ≤ 0.0082, *** p = 0.0001, **** p < 0.0001. (D-E) Rho Inhibitor: 1µg/ml CT04 (Note: no inhibitor pre-treatment). Graph represents the mean ± SD, * p = 0.0285, ** p ≤ 0.0095, **** p < 0.0001. (F-G) ROCK Inhibitor: 10µM Y-27632. Graph represents the mean ± SD, * p ≤ 0.0384, ** p ≤ 0.0016, **** p < 0.0001. (H-1) Rac Inhibitor: 25µM <t>EHT1864.</t> Graph represents the mean ± SD, * p = 0.0120, *** p = 0.0002, **** p < 0.0001.
Hy 100462 Eht 1864 Medchemexpress, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hy 100462 eht 1864 medchemexpress/product/MedChemExpress
Average 93 stars, based on 1 article reviews
hy 100462 eht 1864 medchemexpress - by Bioz Stars, 2026-03
93/100 stars
  Buy from Supplier
hy 16659 nsc 23766 trihydrochloride medchemexpress  (MedChemExpress)
94
MedChemExpress hy 16659 nsc 23766 trihydrochloride medchemexpress
(A) Signaling schematic representing the regulation by PIP5K1C/Rho/ROCK/Rac signaling. (B-I) Average migration of NE-1 and KO-BRCA1 pools in transwell migration assay. Vehicle (ethanol), 10nM R5020, or 10nM R5020 + inhibitor combo treatment for 6-hour migration timepoint, which includes a prior 24-hour pre-treatment of either vehicle (ethanol), 10nM R5020, or 10nM R5020 + inhibitor treatment, respectively. 10% FBS used as chemoattractant. Representative bright-field images to the side of each graph taken at 100µm magnification. (B-C) PIP5K1C Inhibitor: 10µM UNC3230. Graph represents the mean ± SD, * p = 0.0248, ** p ≤ 0.0082, *** p = 0.0001, **** p < 0.0001. (D-E) Rho Inhibitor: 1µg/ml CT04 (Note: no inhibitor pre-treatment). Graph represents the mean ± SD, * p = 0.0285, ** p ≤ 0.0095, **** p < 0.0001. (F-G) ROCK Inhibitor: 10µM Y-27632. Graph represents the mean ± SD, * p ≤ 0.0384, ** p ≤ 0.0016, **** p < 0.0001. (H-1) Rac Inhibitor: 25µM <t>EHT1864.</t> Graph represents the mean ± SD, * p = 0.0120, *** p = 0.0002, **** p < 0.0001.
Hy 16659 Nsc 23766 Trihydrochloride Medchemexpress, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/hy 16659 nsc 23766 trihydrochloride medchemexpress/product/MedChemExpress
Average 94 stars, based on 1 article reviews
hy 16659 nsc 23766 trihydrochloride medchemexpress - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier

Image Search Results


(A) Signaling schematic representing the regulation by PIP5K1C/Rho/ROCK/Rac signaling. (B-I) Average migration of NE-1 and KO-BRCA1 pools in transwell migration assay. Vehicle (ethanol), 10nM R5020, or 10nM R5020 + inhibitor combo treatment for 6-hour migration timepoint, which includes a prior 24-hour pre-treatment of either vehicle (ethanol), 10nM R5020, or 10nM R5020 + inhibitor treatment, respectively. 10% FBS used as chemoattractant. Representative bright-field images to the side of each graph taken at 100µm magnification. (B-C) PIP5K1C Inhibitor: 10µM UNC3230. Graph represents the mean ± SD, * p = 0.0248, ** p ≤ 0.0082, *** p = 0.0001, **** p < 0.0001. (D-E) Rho Inhibitor: 1µg/ml CT04 (Note: no inhibitor pre-treatment). Graph represents the mean ± SD, * p = 0.0285, ** p ≤ 0.0095, **** p < 0.0001. (F-G) ROCK Inhibitor: 10µM Y-27632. Graph represents the mean ± SD, * p ≤ 0.0384, ** p ≤ 0.0016, **** p < 0.0001. (H-1) Rac Inhibitor: 25µM EHT1864. Graph represents the mean ± SD, * p = 0.0120, *** p = 0.0002, **** p < 0.0001.

Journal: bioRxiv

Article Title: Depletion of BRCA1 Potentiates Progestin-Induced Cytoskeletal Changes in an Ovarian Cancer Cell Model

doi: 10.64898/2026.01.02.697409

Figure Lengend Snippet: (A) Signaling schematic representing the regulation by PIP5K1C/Rho/ROCK/Rac signaling. (B-I) Average migration of NE-1 and KO-BRCA1 pools in transwell migration assay. Vehicle (ethanol), 10nM R5020, or 10nM R5020 + inhibitor combo treatment for 6-hour migration timepoint, which includes a prior 24-hour pre-treatment of either vehicle (ethanol), 10nM R5020, or 10nM R5020 + inhibitor treatment, respectively. 10% FBS used as chemoattractant. Representative bright-field images to the side of each graph taken at 100µm magnification. (B-C) PIP5K1C Inhibitor: 10µM UNC3230. Graph represents the mean ± SD, * p = 0.0248, ** p ≤ 0.0082, *** p = 0.0001, **** p < 0.0001. (D-E) Rho Inhibitor: 1µg/ml CT04 (Note: no inhibitor pre-treatment). Graph represents the mean ± SD, * p = 0.0285, ** p ≤ 0.0095, **** p < 0.0001. (F-G) ROCK Inhibitor: 10µM Y-27632. Graph represents the mean ± SD, * p ≤ 0.0384, ** p ≤ 0.0016, **** p < 0.0001. (H-1) Rac Inhibitor: 25µM EHT1864. Graph represents the mean ± SD, * p = 0.0120, *** p = 0.0002, **** p < 0.0001.

Article Snippet: Where applicable, cells were treated with the following reagents at the indicated concentrations: 10nM R5020 (Perkin Elmer, NLP004005MG), 10μM UNC3230 (Med Chem Express, HY-110150), 1μg/ml Rho Inhibitor I (Cytoskeleton, Inc, CT04), 10μM Y27632 dihydrochloride (Med Chem Express, HY-10583), and 25μM EHT1864 (Med Chem Express, HY-16659).

Techniques: Migration, Transwell Migration Assay